Defy Medical vs Ulo: Which TRT Clinic Is Better in 2026?
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Short answer
Defy Medical wins overall, scoring 7.9/10 vs 7.8/10, mainly on clinical oversight and price & value.
Defy Medical wins overall, scoring 7.9/10 vs 7.8/10.
Operating since 2013. Physician-led protocols with injections, cream, pellets and HCG.
Price on consultation
Visit Defy Medical
All-inclusive TRT at $159/mo with a choice of injection, topical or oral.
from $159/mo regular price, no long-term contract
Visit UloDefy Medical vs Ulo, side by side
| Feature | Defy Medical | Ulo |
|---|---|---|
| Our score | 7.9/10 | 7.8/10 |
| Starting price | Price on consultation | $159/mo regular price, no long-term contract |
| Treatment types | injections, cream, pellets, HCG | injections, cream, oral |
| Best for | Best Clinical Oversight | Best Full-Service |
| Overall ranking | #4 | #6 |
| Price & Value (25%) | 6.0 | 7.5 |
| Clinical Oversight (25%) | 9.5 | 7.5 |
| Treatment Options (20%) | 9.0 | 8.0 |
| User Experience (15%) | 8.0 | 8.0 |
| Transparency (15%) | 6.5 | 8.0 |
Sources: Defy Medical pricing verified on defymedical.com, Ulo pricing verified on ulo.co
Defy Medical vs Ulo: plans, price and what's included
Ulo serves 1 that Defy Medical excludes (MS). Both offer injections and cream. Only Defy Medical lists pellets and HCG; only Ulo lists oral.
| Defy Medical | Ulo | |
|---|---|---|
| Starting price | Price on consultation | from $159/mo regular price, no long-term contract |
| Plans it publishes | One published rate | One published rate |
| Commitment | No subscription or contract; you pay per service. (defymedical.com, read Oct 14, 2026) | No long-term contract or cancellation fee; 12-month plans are sold at a discount. (ulo.co, read Oct 14, 2026) |
| Labs | Not stated by the clinic (defymedical.com, read Sep 11, 2026) | Initial and follow-up labs included (ulo.co, read Sep 11, 2026) |
| What the price covers | Total not verified | Rate holds? Not stated |
| First month | Not modeled | $159 |
| 12 months, no commitment | Not modeled | $1,908 |
| Cancelling | There is no subscription to cancel. All sales are final; billing errors are credited to your account rather than refunded. (defymedical.com, read Oct 14, 2026) | Pause or cancel at any time. Prescriptions go to processing immediately, so an order cannot be cancelled before it ships. Returns within 30 days of delivery are refunded for that month's product only. (ulo.co, read Oct 14, 2026) |
| Formats | injections, cream, pellets, HCG | injections, cream, oral |
| States served | 49 of 51 (not: MS) (not confirmed: DC) (defymedical.com, read Oct 9, 2026) | 50 of 51 (not confirmed: DC) (ulo.co, read Oct 9, 2026) |
First-month and 12-month figures come from our 12-month cost model, at each clinic's no-commitment rate. “About per year” for a prepaid plan is our arithmetic on the billing cycle the clinic prints.
Who should pick which
Pick Defy Medical if
- you want pellets or HCG, which Ulo does not list
Pick Ulo if
- you live in MS, which Ulo serves and Defy Medical does not
- you want oral, which Defy Medical does not list
- you want every lab panel inside the price
- you want no commitment
Pros & cons
Defy Medical
Pros
- + Physician-led, operating since 2013
- + Comprehensive bloodwork & protocols
- + Injections, cream, pellets and HCG
Cons
- − Not available in 1 state
- − Weaker on Price & Value (6.0 vs 7.5/10)
- − Weaker on Transparency (6.5 vs 8.0/10)
Ulo
Pros
- + Full-service, accessible model
- + Clear upfront subscription
- + Streamlined onboarding
Cons
- − Weaker on Clinical Oversight (7.5 vs 9.5/10)
- − Weaker on Treatment Options (8.0 vs 9.0/10)
The bottom line
After scoring all 39 clinics on our 5-criterion rubric (price & value, clinical oversight, treatment options, user experience and transparency), Defy Medical (7.9/10) comes out ahead of Ulo (7.8/10). But the right choice still depends on what matters most to you.
Choose Defy Medical if you want best clinical oversight. Price on consultation.
Visit Defy Medical →Choose Ulo if you want best full-service. From $159/mo regular price, no long-term contract.
Visit Ulo →Editor's overall pick
Not sold on either? Our highest-rated clinic overall is Male Excel (8.1/10), from $99/mo membership; medication billed on top. Read the review →
Ready to start TRT?
Our verdict for this matchup is Defy Medical.
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How we score: every clinic is rated on five weighted criteria from documented evidence. Prices are checked weekly by an automated job against each clinic's live page; a price unconfirmed for 45 days is automatically relabeled “Last confirmed” instead of “Verified.” Scores are never influenced by affiliate commissions. “Visit” buttons are affiliate links that support our work. Educational information only. Not medical advice.