TTRT Picks

Defy Medical vs Hone Health: Which TRT Clinic Is Better in 2026?

✓ 39 clinics scored independently✓ Checked weekly against each clinic's live page✓ Scores from evidence · partners first at equal scores

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Short answer

Defy Medical and Hone Health tie at 7.9/10, so it comes down to transparency and clinical oversight. Hone Health is listed first because it is an active affiliate partner. Partnership does not change either score.

Tied: Defy Medical vs Hone Health

Tied at 7.9/10. Hone Health is listed first because it is an active affiliate partner. Partnership does not change either score.

Hone Health · from $155/mo membership; medication billed on top

#4 of 39

Defy Medical

7.9

Operating since 2013. Physician-led protocols with injections, cream, pellets and HCG.

Price on consultation

Visit Defy Medical
Winner
#3 of 39

Hone HealthHone Health

7.9

Hone Health offers online TRT with testosterone injections, cream or troches. Its testosterone page lists Premium membership at $155 a month, plus injectable medication from $28 a month. That combination starts at $183 a month before initial testing. This review explains the membership, medication charges, lab costs and cancellation terms.

from $155/mo membership; medication billed on top

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Defy Medical vs Hone Health: what actually matters

Hone Health's Premium tier is $155 a month. But that figure is a membership fee, not a total: medication is billed on top and isn't itemized anywhere on Hone's site. Defy Medical doesn't publish a number at all. Neither clinic gives you a real all-in figure before you commit, so a "who's cheaper" verdict here would be fabricated either way. We're not writing one.

What separates them is depth versus polish. Defy Medical is the highest clinically-rated clinic in our database (9.5/10), running since 2013 with injections, cream, pellets, and HCG, built for men who want a physician managing a complex hormonal picture. Hone Health leans into experience: at-home lab kits, a well-reviewed app and dashboard, and the higher experience score in this pairing (8.5/10 vs Defy's 8.0/10), though its clinical-oversight score (8.5/10) trails Defy's.

State access matters too: Hone Health's TRT is unavailable in 14 states plus DC, including Pennsylvania and New Jersey. A wide list. Defy Medical has no state restrictions in our data. If broad availability and clinical depth matter most, Defy Medical is the stronger case; if a slick at-home testing experience is the priority and you're in a state Hone actually serves, it's a real contender.

Defy Medical vs Hone Health, side by side

FeatureDefy MedicalHone Health
Our score7.9/107.9/10
Starting pricePrice on consultation$155/mo membership; medication billed on top
Treatment typesinjections, cream, pellets, HCGinjections, cream, troches, clomiphene, enclomiphene, ancillaries, at-home labs
Best forBest Clinical OversightBest App Experience
Overall ranking#4#3
Price & Value (25%)6.06.0
Clinical Oversight (25%)9.58.5
Treatment Options (20%)9.08.5
User Experience (15%)8.08.5
Transparency (15%)6.58.5

Sources: Defy Medical pricing verified on defymedical.com, Hone Health pricing verified on honehealth.com

Defy Medical vs Hone Health: plans, price and what's included

Defy Medical serves 14 states that Hone Health excludes (AL, AK, AR, CT, DE, KS, LA, MN, NH, NJ, ND, PA, RI, SC); Hone Health serves 1 that Defy Medical excludes (MS). Both offer injections and cream. Only Defy Medical lists pellets and HCG; only Hone Health lists troches and clomiphene and enclomiphene and ancillaries and at-home labs.

Defy MedicalHone Health
Starting pricePrice on consultationfrom $155/mo membership; medication billed on top
Plans it publishesOne published rateOne published rate
CommitmentNo subscription or contract; you pay per service. (defymedical.com, read Oct 14, 2026)No commitment. (honehealth.com, read Oct 14, 2026)
LabsNot stated by the clinic (defymedical.com, read Sep 11, 2026)Initial labs billed separately; follow-up labs included (honehealth.com, read Sep 24, 2026)
What the price coversTotal not verifiedMembership excludes medication
First monthNot modeled$248
12 months, no commitmentNot modeled$2,261
CancellingThere is no subscription to cancel. All sales are final; billing errors are credited to your account rather than refunded. (defymedical.com, read Oct 14, 2026)Cancel at any time, per the plan page. We found no published refund terms on the pages we read. (honehealth.com, read Oct 14, 2026)
Formatsinjections, cream, pellets, HCGinjections, cream, troches, clomiphene, enclomiphene, ancillaries, at-home labs
States served49 of 51 (not: MS) (not confirmed: DC) (defymedical.com, read Oct 9, 2026)36 of 51 (not: AL, AK, AR, CT, DE, DC, KS, LA, MN, NH, NJ, ND, PA, RI, SC) (help.honehealth.com, read Oct 11, 2026)

First-month and 12-month figures come from our 12-month cost model, at each clinic's no-commitment rate. “About per year” for a prepaid plan is our arithmetic on the billing cycle the clinic prints.

Who should pick which

Pick Defy Medical if

  • you live in one of the 14 states Hone Health excludes, which Defy Medical serves and Hone Health does not
  • you want pellets or HCG, which Hone Health does not list

Pick Hone Health if

  • you live in MS, which Hone Health serves and Defy Medical does not
  • you want troches or clomiphene or enclomiphene or ancillaries or at-home labs, which Defy Medical does not list
  • you want no commitment

Pros & cons

Defy Medical

Pros

  • + Physician-led, operating since 2013
  • + Comprehensive bloodwork & protocols
  • + Injections, cream, pellets and HCG

Cons

  • − Not available in 1 state
  • − Weaker on Transparency (6.5 vs 8.5/10)
  • − Weaker on User Experience (8.0 vs 8.5/10)

Hone Health

Pros

  • + Follow-up lab testing included in the membership (first lab test $65)
  • + Ongoing physician oversight
  • + Polished app & dashboard

Cons

  • − Not available in 15 states
  • − Weaker on Clinical Oversight (8.5 vs 9.5/10)
  • − Weaker on Treatment Options (8.5 vs 9.0/10)

The bottom line

After scoring all 39 clinics on our 5-criterion rubric (price & value, clinical oversight, treatment options, user experience and transparency), Defy Medical and Hone Health are tied at 7.9/10. Hone Health is listed first because it is an active affiliate partner. Partnership does not change either score. Beyond the score, there is no clear overall winner here, so the right choice comes down to what matters most to you.

Choose Defy Medical if you want best clinical oversight. Price on consultation.

Visit Defy Medical →

Choose Hone Health if you want best app experience. From $155/mo membership; medication billed on top.

Visit →

Editor's overall pick

Not sold on either? Our highest-rated clinic overall is Male Excel (8.1/10), from $99/mo membership; medication billed on top. Read the review →

Ready to start TRT?

Defy Medical and Hone Health are essentially tied. Either is a solid choice.

Hone Health · from $155/mo membership; medication billed on topVisit →
See full rankings

Related comparisons

Male Excel vs Hone Health→Male Excel vs Defy Medical→1st Optimal vs Hone Health→1st Optimal vs Defy Medical→Rugiet vs Hone Health→Hone Health vs Ulo→

Top picks

Male Excel

8.1

from $99/mo membership; medication billed on top

1st Optimal

8.1

from $169/mo with a 120-day minimum, billed monthly

Hone Health

7.9

from $155/mo membership; medication billed on top

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How we score: every clinic is rated on five weighted criteria from documented evidence. Prices are checked weekly by an automated job against each clinic's live page; a price unconfirmed for 45 days is automatically relabeled “Last confirmed” instead of “Verified.” Scores are never influenced by affiliate commissions. “Visit” buttons are affiliate links that support our work. Educational information only. Not medical advice.