TTRT Picks

Defy Medical vs Keeps TRT: Which TRT Clinic Is Better in 2026?

✓ 39 clinics scored independently✓ Checked weekly against each clinic's live page✓ Scores from evidence · partners first at equal scores

Summarize this page with

Short answer

Defy Medical wins overall, scoring 7.9/10 vs 6.3/10, mainly on treatment options and clinical oversight.

Our pick: Defy Medical

Defy Medical wins overall, scoring 7.9/10 vs 6.3/10.

Winner
#4 of 39

Defy Medical

7.9

Operating since 2013. Physician-led protocols with injections, cream, pellets and HCG.

Price on consultation

Visit Defy Medical
#27 of 39

Keeps TRTKeeps TRT

6.3

Well-known brand (from hair loss) with a simple digital sign-up. A promotional $49 covers labs, consult and plan, but ongoing treatment cost isn't shown until after the eligibility quiz.

Price on consultation

Visit Keeps TRT

Defy Medical vs Keeps TRT: what actually matters

Neither Defy Medical nor Keeps TRT gives you a real ongoing price before you commit. Keeps TRT's only public figure, $49, covers just the initial bloodwork, consultation, and plan; medication and membership costs stay hidden behind an eligibility quiz we couldn't complete on the site's behalf. Defy Medical doesn't publish anything at all. There's no honest way to call either one "cheaper."

The two clinics are aimed at different men. Defy Medical has the highest clinical-oversight score in our database (9.5/10), running since 2013 with injections, cream, pellets, and HCG, built for complex, physician-managed protocols. Keeps TRT trades on brand recognition (it's the same company known for hair-loss treatment) and a fast, simple digital sign-up; its clinical score is more modest at 7.0/10, and its treatment range is narrower. Injectable testosterone cypionate plus two orally disintegrating tablets, testosterone and enclomiphene.

Transparency also splits them: Defy Medical scores 8.5/10 on our transparency criterion versus Keeps TRT's 7.0/10, partly because Keeps discloses even less about what happens after the $49 intake step. If you want an established, comprehensive clinical relationship, Defy Medical is the stronger case. If a familiar brand and the easiest possible sign-up matter more than clinical depth, Keeps TRT fits that instead.

Defy Medical vs Keeps TRT, side by side

FeatureDefy MedicalKeeps TRT
Our score7.9/106.3/10
Starting pricePrice on consultationPrice on consultation
Treatment typesinjections, cream, pellets, HCGinjections, oral testosterone (ODT), enclomiphene
Best forBest Clinical OversightBest for Beginners
Overall ranking#4#27
Price & Value (25%)6.06.0
Clinical Oversight (25%)9.57.0
Treatment Options (20%)9.06.0
User Experience (15%)8.08.5
Transparency (15%)6.54.0

Sources: Defy Medical pricing verified on defymedical.com, Keeps TRT pricing verified on jointitan.com

Defy Medical vs Keeps TRT: plans, price and what's included

Both offer injections. Only Defy Medical lists cream and pellets and HCG; only Keeps TRT lists oral testosterone (ODT) and enclomiphene.

Defy MedicalKeeps TRT
Starting pricePrice on consultationPrice on consultation
Plans it publishesOne published rateOne published rate
CommitmentNo subscription or contract; you pay per service. (defymedical.com, read Oct 14, 2026)No minimum term stated. The membership fee is charged every 84 days and medication every 12 weeks until you cancel. (jointitan.com, read Oct 14, 2026)
LabsNot stated by the clinic (defymedical.com, read Sep 11, 2026)Initial and follow-up labs included (jointitan.com, read Sep 11, 2026)
What the price coversTotal not verifiedTotal not verified
First monthNot modeledNot modeled
12 months, no commitmentNot modeledNot modeled
CancellingThere is no subscription to cancel. All sales are final; billing errors are credited to your account rather than refunded. (defymedical.com, read Oct 14, 2026)Email trt@keeps.com at least 48 hours before the current billing cycle ends. Membership and medication fees are not refunded once charged. (jointitan.com, read Oct 14, 2026)
Formatsinjections, cream, pellets, HCGinjections, oral testosterone (ODT), enclomiphene
States served49 of 51 (not: MS) (not confirmed: DC) (defymedical.com, read Oct 9, 2026)State list not on file

First-month and 12-month figures come from our 12-month cost model, at each clinic's no-commitment rate. “About per year” for a prepaid plan is our arithmetic on the billing cycle the clinic prints.

Who should pick which

Pick Defy Medical if

  • you want cream or pellets or HCG, which Keeps TRT does not list

Pick Keeps TRT if

  • you want oral testosterone (ODT) or enclomiphene, which Defy Medical does not list
  • you want every lab panel inside the price

Pros & cons

Defy Medical

Pros

  • + Physician-led, operating since 2013
  • + Comprehensive bloodwork & protocols
  • + Injections, cream, pellets and HCG

Cons

  • − Not available in 1 state
  • − Weaker on User Experience (8.0 vs 8.5/10)

Keeps TRT

Pros

  • + Trusted, established brand
  • + Fast digital onboarding
  • + $49 promotional entry covers bloodwork, consult and plan

Cons

  • − Weaker on Treatment Options (6.0 vs 9.0/10)
  • − Weaker on Clinical Oversight (7.0 vs 9.5/10)
  • − Weaker on Transparency (4.0 vs 6.5/10)

The bottom line

After scoring all 39 clinics on our 5-criterion rubric (price & value, clinical oversight, treatment options, user experience and transparency), Defy Medical (7.9/10) comes out ahead of Keeps TRT (6.3/10). But the right choice still depends on what matters most to you.

Choose Defy Medical if you want best clinical oversight. Price on consultation.

Visit Defy Medical →

Choose Keeps TRT if you want best for beginners. Price on consultation.

Visit Keeps TRT →

Editor's overall pick

Not sold on either? Our highest-rated clinic overall is Male Excel (8.1/10), from $99/mo membership; medication billed on top. Read the review →

Ready to start TRT?

Our verdict for this matchup is Defy Medical.

Related comparisons

Male Excel vs Defy Medical→Male Excel vs Keeps TRT→1st Optimal vs Defy Medical→1st Optimal vs Keeps TRT→Defy Medical vs Hone Health→Hone Health vs Keeps TRT→

Top picks

Male Excel

8.1

from $99/mo membership; medication billed on top

1st Optimal

8.1

from $169/mo with a 120-day minimum, billed monthly

Hone Health

7.9

from $155/mo membership; medication billed on top

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How we score: every clinic is rated on five weighted criteria from documented evidence. Prices are checked weekly by an automated job against each clinic's live page; a price unconfirmed for 45 days is automatically relabeled “Last confirmed” instead of “Verified.” Scores are never influenced by affiliate commissions. “Visit” buttons are affiliate links that support our work. Educational information only. Not medical advice.