TTRT Picks

1st Optimal vs Keeps TRT: Which TRT Clinic Is Better in 2026?

✓ 39 clinics scored independently✓ Checked weekly against each clinic's live page✓ Scores from evidence · partners first at equal scores

Summarize this page with

Short answer

1st Optimal wins overall, scoring 8.1/10 vs 6.3/10, mainly on transparency and treatment options.

Our pick: 1st Optimal

1st Optimal wins overall, scoring 8.1/10 vs 6.3/10.

Winner
#2 of 39

1st Optimal

8.1

Maps your hormones within metabolic, thyroid and lifestyle context. Thorough, with higher upfront labs.

from $169/mo with a 120-day minimum, billed monthly

Visit 1st Optimal
#27 of 39

Keeps TRTKeeps TRT

6.3

Well-known brand (from hair loss) with a simple digital sign-up. A promotional $49 covers labs, consult and plan, but ongoing treatment cost isn't shown until after the eligibility quiz.

Price on consultation

Visit Keeps TRT

1st Optimal vs Keeps TRT, side by side

Feature1st OptimalKeeps TRT
Our score8.1/106.3/10
Starting price$169/mo with a 120-day minimum, billed monthlyPrice on consultation
Treatment typesinjections, peptides, comprehensive labsinjections, oral testosterone (ODT), enclomiphene
Best forBest for Comprehensive LabsBest for Beginners
Overall ranking#2#27
Price & Value (25%)7.56.0
Clinical Oversight (25%)8.57.0
Treatment Options (20%)8.06.0
User Experience (15%)8.08.5
Transparency (15%)8.54.0

Sources: 1st Optimal pricing verified on 1stoptimal.com, Keeps TRT pricing verified on jointitan.com

1st Optimal vs Keeps TRT: plans, price and what's included

Both offer injections. Only 1st Optimal lists peptides and comprehensive labs; only Keeps TRT lists oral testosterone (ODT) and enclomiphene.

1st OptimalKeeps TRT
Starting pricefrom $169/mo with a 120-day minimum, billed monthlyPrice on consultation
Plans it publishesOne published rateOne published rate
Commitment120-day minimum, billed monthly. (1stoptimal.com, read Oct 14, 2026)No minimum term stated. The membership fee is charged every 84 days and medication every 12 weeks until you cancel. (jointitan.com, read Oct 14, 2026)
LabsNot stated by the clinic (1stoptimal.com, read Sep 11, 2026)Initial and follow-up labs included (jointitan.com, read Sep 11, 2026)
What the price coversRate holds? Not statedTotal not verified
First month$169Not modeled
12 months, no commitment$2,028Not modeled
CancellingAfter 120 days, submit the membership change request form at least 7 days before the next billing date. Prescribed treatments and telemedicine services are not refunded. (1stoptimal.com, read Oct 14, 2026)Email trt@keeps.com at least 48 hours before the current billing cycle ends. Membership and medication fees are not refunded once charged. (jointitan.com, read Oct 14, 2026)
Formatsinjections, peptides, comprehensive labsinjections, oral testosterone (ODT), enclomiphene
States servedState list not on fileState list not on file

First-month and 12-month figures come from our 12-month cost model, at each clinic's no-commitment rate. “About per year” for a prepaid plan is our arithmetic on the billing cycle the clinic prints.

Who should pick which

Pick 1st Optimal if

  • you want peptides or comprehensive labs, which Keeps TRT does not list

Pick Keeps TRT if

  • you want oral testosterone (ODT) or enclomiphene, which 1st Optimal does not list
  • you want every lab panel inside the price

Pros & cons

1st Optimal

Pros

  • + Deep, context-rich lab work
  • + Metabolic & thyroid screening
  • + Peptide options available

Cons

  • − Weaker on User Experience (8.0 vs 8.5/10)

Keeps TRT

Pros

  • + Trusted, established brand
  • + Fast digital onboarding
  • + $49 promotional entry covers bloodwork, consult and plan

Cons

  • − Weaker on Transparency (4.0 vs 8.5/10)
  • − Weaker on Treatment Options (6.0 vs 8.0/10)
  • − Weaker on Price & Value (6.0 vs 7.5/10)

The bottom line

After scoring all 39 clinics on our 5-criterion rubric (price & value, clinical oversight, treatment options, user experience and transparency), 1st Optimal (8.1/10) comes out ahead of Keeps TRT (6.3/10). But the right choice still depends on what matters most to you.

Choose 1st Optimal if you want best for comprehensive labs. From $169/mo with a 120-day minimum, billed monthly.

Visit 1st Optimal →

Choose Keeps TRT if you want best for beginners. Price on consultation.

Visit Keeps TRT →

Editor's overall pick

Not sold on either? Our highest-rated clinic overall is Male Excel (8.1/10), from $99/mo membership; medication billed on top. Read the review →

Ready to start TRT?

Our verdict for this matchup is 1st Optimal.

Related comparisons

Male Excel vs 1st Optimal→Male Excel vs Keeps TRT→1st Optimal vs Hone Health→1st Optimal vs Defy Medical→1st Optimal vs Rugiet→1st Optimal vs Ulo→

Top picks

Male Excel

8.1

from $99/mo membership; medication billed on top

1st Optimal

8.1

from $169/mo with a 120-day minimum, billed monthly

Hone Health

7.9

from $155/mo membership; medication billed on top

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How we score: every clinic is rated on five weighted criteria from documented evidence. Prices are checked weekly by an automated job against each clinic's live page; a price unconfirmed for 45 days is automatically relabeled “Last confirmed” instead of “Verified.” Scores are never influenced by affiliate commissions. “Visit” buttons are affiliate links that support our work. Educational information only. Not medical advice.