TTRT Picks

1st Optimal vs Hone Health: Which TRT Clinic Is Better in 2026?

✓ 39 clinics scored independently✓ Checked weekly against each clinic's live page✓ Scores from evidence · partners first at equal scores

Summarize this page with

Short answer

1st Optimal wins overall, scoring 8.1/10 vs 7.9/10, mainly on price & value and treatment options. If price is your priority, Hone Health is cheaper at $155/mo membership; medication billed on top.

Our pick: 1st Optimal

1st Optimal wins overall, scoring 8.1/10 vs 7.9/10. If price is your priority, Hone Health is cheaper at $155/mo membership; medication billed on top.

Winner
#2 of 39

1st Optimal

8.1

Maps your hormones within metabolic, thyroid and lifestyle context. Thorough, with higher upfront labs.

from $169/mo with a 120-day minimum, billed monthly

Visit 1st Optimal
#3 of 39

Hone Health

7.9

Seamless onboarding and at-home lab work; medication billed on top of the membership, from $28/mo and itemized per medication.

from $155/mo membership; medication billed on top

Pick the program →

1st Optimal vs Hone Health, side by side

Feature1st OptimalHone Health
Our score8.1/107.9/10
Starting price$169/mo with a 120-day minimum, billed monthly$155/mo membership; medication billed on top
Treatment typesinjections, peptides, comprehensive labsinjections, cream, troches, clomiphene, enclomiphene, ancillaries, at-home labs
Best forBest for Comprehensive LabsBest App Experience
Overall ranking#2#3
Price & Value (25%)7.56.0
Clinical Oversight (25%)8.58.5
Treatment Options (20%)8.08.5
User Experience (15%)8.08.5
Transparency (15%)8.58.5

Sources: 1st Optimal pricing verified on 1stoptimal.com, Hone Health pricing verified on honehealth.com

1st Optimal vs Hone Health: plans, price and what's included

Without committing, 1st Optimal costs $233 less than Hone Health over 12 months ($2,028 against $2,261), and $79 less in the first month. Both offer injections. Only 1st Optimal lists peptides and comprehensive labs; only Hone Health lists cream and troches and clomiphene and enclomiphene and ancillaries and at-home labs.

1st OptimalHone Health
Starting pricefrom $169/mo with a 120-day minimum, billed monthlyfrom $155/mo membership; medication billed on top
Plans it publishesOne published rateOne published rate
Commitment120-day minimum, billed monthly. (1stoptimal.com, read Oct 14, 2026)No commitment. (honehealth.com, read Oct 14, 2026)
LabsNot stated by the clinic (1stoptimal.com, read Sep 11, 2026)Initial labs billed separately; follow-up labs included (honehealth.com, read Sep 24, 2026)
What the price coversRate holds? Not statedMembership excludes medication
First month$169$248
12 months, no commitment$2,028$2,261
CancellingAfter 120 days, submit the membership change request form at least 7 days before the next billing date. Prescribed treatments and telemedicine services are not refunded. (1stoptimal.com, read Oct 14, 2026)Cancel at any time, per the plan page. We found no published refund terms on the pages we read. (honehealth.com, read Oct 14, 2026)
Formatsinjections, peptides, comprehensive labsinjections, cream, troches, clomiphene, enclomiphene, ancillaries, at-home labs
States servedState list not on file36 of 51 (not: AL, AK, AR, CT, DE, DC, KS, LA, MN, NH, NJ, ND, PA, RI, SC) (help.honehealth.com, read Oct 11, 2026)

First-month and 12-month figures come from our 12-month cost model, at each clinic's no-commitment rate. “About per year” for a prepaid plan is our arithmetic on the billing cycle the clinic prints.

Who should pick which

Pick 1st Optimal if

  • you want the lower 12-month cost without committing: about $2,028 against $2,261 for Hone Health, on our cost model
  • you want peptides or comprehensive labs, which Hone Health does not list

Pick Hone Health if

  • you want cream or troches or clomiphene or enclomiphene or ancillaries or at-home labs, which 1st Optimal does not list
  • you want no commitment

Pros & cons

1st Optimal

Pros

  • + Deep, context-rich lab work
  • + Metabolic & thyroid screening
  • + Peptide options available

Cons

  • − Weaker on Treatment Options (8.0 vs 8.5/10)
  • − Weaker on User Experience (8.0 vs 8.5/10)

Hone Health

Pros

  • + Follow-up lab testing included in the membership (first lab test $65)
  • + Ongoing physician oversight
  • + Polished app & dashboard

Cons

  • − Not available in 15 states
  • − Weaker on Price & Value (6.0 vs 7.5/10)

The bottom line

After scoring all 39 clinics on our 5-criterion rubric (price & value, clinical oversight, treatment options, user experience and transparency), 1st Optimal (8.1/10) comes out ahead of Hone Health (7.9/10). But the right choice still depends on what matters most to you.

Choose 1st Optimal if you want best for comprehensive labs. From $169/mo with a 120-day minimum, billed monthly.

Visit 1st Optimal →

Choose Hone Health if you want best app experience. From $155/mo membership; medication billed on top.

Pick the program →

Editor's overall pick

Not sold on either? Our highest-rated clinic overall is Male Excel (8.1/10), from $99/mo membership; medication billed on top. Read the review →

Ready to start TRT?

Our verdict for this matchup is 1st Optimal.

Hone Health · from $155/mo membership; medication billed on topPick the program →
See full rankings

Related comparisons

Male Excel vs 1st Optimal→Male Excel vs Hone Health→1st Optimal vs Defy Medical→1st Optimal vs Rugiet→1st Optimal vs Ulo→1st Optimal vs Fountain TRT→

Top picks

Male Excel

8.1

from $99/mo membership; medication billed on top

1st Optimal

8.1

from $169/mo with a 120-day minimum, billed monthly

Hone Health

7.9

from $155/mo membership; medication billed on top

We email you when a price we track changes.

No spam, no daily digest. Just the clinics you're comparing, when their verified price moves.

How we score: every clinic is rated on five weighted criteria from documented evidence. Prices are checked weekly by an automated job against each clinic's live page; a price unconfirmed for 45 days is automatically relabeled “Last confirmed” instead of “Verified.” Scores are never influenced by affiliate commissions. “Pick the program” buttons are affiliate links that support our work. Educational information only. Not medical advice.