Hone Health vs Defy Medical: Which TRT Clinic Is Better in 2026?
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Short answer
Hone Health and Defy Medical tie at 7.9/10, so it comes down to transparency and clinical oversight.
Hone Health and Defy Medical are essentially tied, 7.9/10 vs 7.9/10.
Hone Health
Seamless onboarding and at-home lab work; medication billed on top of the membership, from $28/mo and itemized per medication.
from $155/mo
Visit Hone HealthDefy Medical
The gold standard since 2013 — physician-led protocols and the widest range of ancillary medications.
Price on consultation
Visit Defy MedicalHone Health vs Defy Medical, side by side
| Feature | Hone Health | Defy Medical |
|---|---|---|
| Our score | 7.9/10 | 7.9/10 |
| Starting price | $155/mo | Price on consultation |
| Treatment types | injections, cream, troches, clomiphene, enclomiphene, ancillaries, at-home labs | injections, cream, pellets, HCG |
| Best for | Best App Experience | Best Clinical Oversight |
| Overall ranking | #5 | #6 |
| Price & Value (25%) | 6.0 | 6.0 |
| Clinical Oversight (25%) | 8.5 | 9.5 |
| Treatment Options (20%) | 8.5 | 9.0 |
| User Experience (15%) | 8.5 | 8.0 |
| Transparency (15%) | 8.5 | 6.5 |
Sources: Hone Health pricing verified on honehealth.com, Defy Medical pricing verified on defymedical.com
Pros & cons
Hone Health
Pros
- + At-home lab testing included
- + Ongoing physician oversight
- + Polished app & dashboard
Cons
- − Not available in 18 states
- − Weaker on Price & Value (6.0/10)
- − Weaker on Clinical Oversight (8.5/10)
Defy Medical
Pros
- + Physician-led, longest track record
- + Comprehensive bloodwork & protocols
- + Widest treatment range
Cons
- − Weaker on Price & Value (6.0/10)
- − Weaker on Transparency (6.5/10)
- − Weaker on User Experience (8.0/10)
The bottom line
After scoring all 32 clinics on our 5-criterion rubric (price & value, clinical oversight, treatment options, user experience and transparency), Hone Health and Defy Medical are essentially tied (7.9 vs 7.9/10) — there is no clear overall winner here, so the right choice comes down to what matters most to you.
Choose Hone Health if you want best app experience — from $155/mo.
Visit Hone Health →Choose Defy Medical if you want best clinical oversight — Price on consultation.
Visit Defy Medical →Editor's overall pick
Not sold on either? Our highest-rated clinic overall is Male Excel (8.1/10), from $99/mo — read the review →
Ready to start TRT?
Hone Health and Defy Medical are essentially tied — either is a solid choice.
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How we score: every clinic is rated on five weighted criteria from documented evidence. Prices are checked weekly by an automated job against each clinic's live page; a price unconfirmed for 45 days is automatically relabeled “Last confirmed” instead of “Verified.” Scores are never influenced by affiliate commissions. “Visit”/“Try” links may be affiliate links that support our work. Educational information only — not medical advice.