TTRT Picks

Hims vs 1st Optimal: Which TRT Clinic Is Better in 2026?

15 clinics scored independently✓ Prices re-verified monthly✓ Commissions never move our rankings
Our pick: Hims

Hims wins overall, scoring 7.6/10 vs 7.6/10.

Winner
#10 of 15

Hims

7.6

Big-brand polish and a smooth app, but currently oral enclomiphene only — injectables expected in 2026.

from $99/mo

Visit Hims
#11 of 15

1st Optimal

7.6

Maps your hormones within metabolic, thyroid and lifestyle context — thorough, with higher upfront labs.

from $166/mo

Visit 1st Optimal

Hims vs 1st Optimal, side by side

FeatureHims1st Optimal
Our score7.6/107.6/10
Starting price$99/mo$166/mo
Treatment typesoral (enclomiphene)injections, peptides, comprehensive labs
Best forBest Brand NameBest for Comprehensive Labs
Overall ranking#10#11
Price & Value (25%)8.56.0
Clinical Oversight (25%)7.58.5
Treatment Options (20%)5.58.0
User Experience (15%)9.08.0
Transparency (15%)7.58.0

Pros & cons

Hims

Pros

  • + Recognized national brand
  • + Excellent digital experience
  • + Bundled meds, labs & shipping

Cons

  • Weaker on Treatment Options (5.5/10)
  • Weaker on Clinical Oversight (7.5/10)
  • Weaker on Transparency (7.5/10)

1st Optimal

Pros

  • + Deep, context-rich lab work
  • + Metabolic & thyroid screening
  • + Peptide options available

Cons

  • Weaker on Price & Value (6.0/10)
  • Weaker on Treatment Options (8.0/10)
  • Weaker on User Experience (8.0/10)

The bottom line

After scoring all 15 clinics on price, clinical oversight, treatment options, experience and transparency, Hims (7.6/10) comes out ahead of 1st Optimal (7.6/10) — but the right choice depends on what matters most to you.

Choose Hims if you want best brand name — from $99/mo.

Visit Hims

Choose 1st Optimal if you want best for comprehensive labs — from $166/mo.

Visit 1st Optimal

Editor's overall pick

Not sold on either? Our highest-rated clinic overall is Defy Medical (8.2/10) from $200/mo — read the review →

Ready to start TRT?

Our verdict for this matchup is Hims.

Related comparisons

Defy Medical vs HimsDefy Medical vs 1st OptimalHone Health vs HimsHone Health vs 1st OptimalPeter MD vs HimsPeter MD vs 1st Optimal

Top picks

Defy Medical

8.2

from $200/mo

Hone Health

8.1

from $129/mo

Peter MD

8.1

from $79/mo

How we score: every clinic is rated on five weighted criteria from documented evidence, re-verified monthly. Scores are never influenced by affiliate commissions. “Visit”/“Try” links may be affiliate links that support our work. Educational information only — not medical advice.