TTRT Picks

Peter MD vs 1st Optimal: Which TRT Clinic Is Better in 2026?

15 clinics scored independently✓ Prices re-verified monthly✓ Commissions never move our rankings
Our pick: Peter MD

Peter MD wins overall, scoring 8.1/10 vs 7.6/10.

Winner
#3 of 15

Peter MD

8.1

All-inclusive bundles from as low as $79/mo on an annual plan — meds, labs and consults in one fee.

from $79/mo

Visit Peter MD
#11 of 15

1st Optimal

7.6

Maps your hormones within metabolic, thyroid and lifestyle context — thorough, with higher upfront labs.

from $166/mo

Visit 1st Optimal

Peter MD vs 1st Optimal, side by side

FeaturePeter MD1st Optimal
Our score8.1/107.6/10
Starting price$79/mo$166/mo
Treatment typesinjections, creaminjections, peptides, comprehensive labs
Best forCheapestBest for Comprehensive Labs
Overall ranking#3#11
Price & Value (25%)9.56.0
Clinical Oversight (25%)7.58.5
Treatment Options (20%)7.58.0
User Experience (15%)8.08.0
Transparency (15%)7.58.0

Pros & cons

Peter MD

Pros

  • + Cheapest with annual commitment
  • + All-inclusive single monthly fee
  • + Bundled labs & consults

Cons

  • Not available in 2 states
  • Weaker on Clinical Oversight (7.5/10)
  • Weaker on Treatment Options (7.5/10)

1st Optimal

Pros

  • + Deep, context-rich lab work
  • + Metabolic & thyroid screening
  • + Peptide options available

Cons

  • Weaker on Price & Value (6.0/10)
  • Weaker on Treatment Options (8.0/10)
  • Weaker on User Experience (8.0/10)

The bottom line

After scoring all 15 clinics on price, clinical oversight, treatment options, experience and transparency, Peter MD (8.1/10) comes out ahead of 1st Optimal (7.6/10) — but the right choice depends on what matters most to you.

Choose Peter MD if you want cheapest — from $79/mo.

Visit Peter MD

Choose 1st Optimal if you want best for comprehensive labs — from $166/mo.

Visit 1st Optimal

Editor's overall pick

Not sold on either? Our highest-rated clinic overall is Defy Medical (8.2/10) from $200/mo — read the review →

Ready to start TRT?

Our verdict for this matchup is Peter MD.

Related comparisons

Defy Medical vs Peter MDDefy Medical vs 1st OptimalHone Health vs Peter MDHone Health vs 1st OptimalPeter MD vs TRT NationPeter MD vs Male Excel

Top picks

Defy Medical

8.2

from $200/mo

Hone Health

8.1

from $129/mo

Peter MD

8.1

from $79/mo

How we score: every clinic is rated on five weighted criteria from documented evidence, re-verified monthly. Scores are never influenced by affiliate commissions. “Visit”/“Try” links may be affiliate links that support our work. Educational information only — not medical advice.